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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

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[Assisted hatching following embryo implantation failure].

Esperanza Carballo Mondragón1, Leonor Durán Monterrosas, Jorge A Campos Cañas

  • 1Laboratorio de Reproducción Asistida, Centro Mexicano de Fertilidad, Huixquilucan, Estado de México, México.

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|October 24, 2012
PubMed
Summary

Assisted hatching improved pregnancy rates in patients with prior implantation failure. Women aged 35-39 experienced the highest success with this assisted reproductive technology.

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Area of Science:

  • Reproductive Medicine
  • In Vitro Fertilization
  • Embryology

Background:

  • Assisted hatching (AH) enhances implantation rates in specific patient groups with poor prognosis.
  • This study investigates AH's impact on patients with previous implantation failures, stratified by age.

Purpose of the Study:

  • To compare pregnancy rates between patients undergoing in vitro fertilization (IVF) with AH after implantation failure and those attempting IVF without AH.
  • To analyze these rates across different age demographics.

Main Methods:

  • A retrospective study of patients undergoing AH between January 2008 and December 2009.
  • Patients were categorized into three age groups: >35 years (Group I), 35-39 years (Group II), and >40 years (Group III).

Main Results:

  • Group II (35-39 years) demonstrated the highest pregnancy rate at 30%.
  • Patients utilizing AH achieved a 20% pregnancy rate, whereas the control group (no AH) reported no pregnancies.

Conclusions:

  • Assisted hatching appears beneficial for patients experiencing implantation failure during IVF.
  • The 35-39 age group showed the most promising outcomes with assisted hatching.