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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
[Efficacy of immunomodulators in children with respiratory diseases in environmentally poor areas]
Insights
Isoprinosine (inosine pranobex) improved clinical outcomes and immune function in children with respiratory diseases. This antiviral and immunomodulatory drug demonstrated safety and efficacy in treating bronchopulmonary conditions.
Area of Science:
- Pediatrics
- Immunology
- Pharmacology
Background:
- Bronchopulmonary diseases are common in children.
- Effective antiviral and immunomodulatory treatments are needed.
Purpose of the Study:
- To evaluate the clinical efficacy and safety of Isoprinosine (inosine pranobex) in pediatric bronchopulmonary diseases.
- To assess its impact on clinical outcomes and immune status.
Main Methods:
- A study involving 152 children with acute or recurrent respiratory diseases.
- Isoprinosine was used as part of combined treatment.
Main Results:
- Positive clinical changes were observed in children treated with Isoprinosine.
- An improved immunogram (immune system function) was noted.
Conclusions:
- Isoprinosine is a safe and effective option for treating pediatric bronchopulmonary diseases.
- It offers benefits in both clinical improvement and immune modulation.
Abstract:
The authors evaluated the clinical efficacy and safety of the antiviral and immunomodulatory drug Isoprinosine (inosine pranobex, Teva Pharmaceutical Industries, Ltd) in the treatment of bronchopulmonary diseases in children. One hundred and fifty-two children with acute respiratory diseases and an exacerbation of recurrent respiratory diseases were followed up. The use of Isoprinosine in their combined treatment showed both positive clinical changes and a better immunogram.
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