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Related Experiment Video

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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Lower urinary tract function in childhood; normal development and common functional disturbances.

T Nevéus¹, U Sillén

¹Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. tryggve.neveus@kbh.uu.se

Acta Physiologica (Oxford, England)

|October 24, 2012

Summary

This summary is machine-generated.

Childhood bladder dysfunction, including daytime incontinence and nocturnal enuresis, affects 5-10% of children. These conditions, often due to detrusor overactivity or dyscoordination, can persist into adulthood.

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Area of Science:

Urology
Pediatric Urology
Developmental Biology

Background:

Bladder development initiates early in gestation (weeks 4-6), with detrusor muscle formation by weeks 9-12.
Infants possess higher central nervous system (CNS) centers involved in micturition at birth.
Early childhood voiding may be incomplete due to detrusor-sphincter dyscoordination, resolving with bladder control attainment.

Purpose of the Study:

To offer background knowledge on early bladder function development.
To detail common childhood bladder disturbances.
To inform researchers and clinicians managing adult lower urinary tract issues.

Main Methods:

Literature review of bladder development and childhood voiding disturbances.
Synthesis of information on the etiology of daytime incontinence and nocturnal enuresis.
Analysis of the long-term implications of pediatric bladder problems.

Main Results:

Detrusor-sphincter dyscoordination is common in early childhood voiding.
Daytime incontinence (5-10% of 7-year-olds) is often linked to detrusor overactivity.
Nocturnal enuresis results from nocturnal polyuria and/or detrusor overactivity with high arousal thresholds.

Conclusions:

Childhood bladder problems are significant risk factors for adult lower urinary tract dysfunction.
Understanding pediatric bladder development is crucial for managing adult conditions.
Detrusor overactivity and high arousal thresholds are key factors in childhood incontinence and enuresis.