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Updated: May 17, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Perioperative oxygen toxicity
Andrew B Lumb1, Laura J Walton
1Department of Anaesthesia, St James's University Hospital, Leeds, United Kingdom. a.lumb@leeds.ac.uk
Abstract:
This article challenges the use of hyperoxia in the perioperative period. It describes the biochemical and physiologic basis for both the direct and indirect adverse effects of oxygen. The reasons for using hyperoxia in the perioperative period are critically evaluated, and the evidence and guidelines for oxygen use in common acute medical conditions are reviewed.
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