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Updated: May 17, 2026
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Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Pelvic massive allograft reconstruction after bone tumour resection.
Domenico Campanacci1, Sara Chacon, Nicola Mondanelli
1Ortopedia Oncologica e Ricostruttiva, Azienda Ospedaliera Universitaria Careggi, Florence, Italy.
International Orthopaedics
|October 24, 2012
Summary
Pelvic allografts offer a viable reconstruction method after tumor resection, but careful patient selection is crucial due to significant surgical morbidity and functional outcomes.
Area of Science:
- Orthopedic oncology
- Musculoskeletal tumor surgery
- Reconstructive surgery
Background:
- Pelvic tumors often necessitate extensive surgical resection.
- Reconstruction following pelvic tumor resection presents significant challenges.
- Massive allografts are utilized for pelvic reconstruction.
Purpose of the Study:
- To retrospectively review patients undergoing pelvic tumor resection and allograft reconstruction.
- To evaluate patient and implant survival, functional outcomes, and surgical morbidity.
Main Methods:
- Retrospective review of 33 patients treated with pelvic tumor resection and massive allograft reconstruction.
- Data collected on patient demographics, tumor type, surgical extent, and follow-up outcomes.
- Analysis of survival rates, functional scores (MSTS), and complication rates.
Main Results:
- High morbidity observed, including deep infections (15%), hip dislocations (18%), and sciatic nerve palsy (24%).
- Implant survival was 87.3% at last follow-up.
- Cumulative patient survival was 41.5% at 5 and 10 years; functional scores were 70% (acetabulum preserved) vs. 61% (acetabulum resected).
Conclusions:
- Pelvic allografts are a valid option for reconstruction after pelvic tumor resection.
- High rates of morbidity necessitate careful patient selection.
- Outcomes highlight the trade-offs between reconstruction and potential complications.
