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Photopatterning Proteins and Cells in Aqueous Environment Using TiO2 Photocatalysis
Published on: October 26, 2015
Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes
Yun Zhao1, Josephine L C Howe, Zhang Yu
1School of Materials Science and Engineering, Nanyang Technological University, Singapore.
Small (Weinheim an Der Bergstrasse, Germany)
|October 24, 2012
Abstract:
Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles.
