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Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
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Ischemic colitis in an endurance runner.

Chase Grames1, Cristóbal S Berry-Cabán

  • 1Department of Family Medicine, Womack Army Medical Center, Fort Bragg, NC 28310, USA.

Case Reports in Gastrointestinal Medicine
|October 24, 2012
PubMed
Summary
This summary is machine-generated.

Endurance athletes may experience ischemic colitis, a condition causing bloody diarrhea, particularly after strenuous exercise. Discontinuing nonsteroidal anti-inflammatory drugs (NSAIDs) can resolve symptoms and allow a return to athletic activity.

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Area of Science:

  • Gastroenterology
  • Sports Medicine
  • Exercise Physiology

Background:

  • Strenuous endurance exercise, like marathons, can precipitate gastrointestinal distress.
  • Ischemic colitis, characterized by bloody diarrhea, is a potential complication in athletes.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used by athletes and may exacerbate ischemic colitis.

Purpose of the Study:

  • To describe a case of ischemic colitis in a marathon runner.
  • To review the pathophysiology, diagnosis, and management of exercise-induced ischemic colitis.
  • To highlight the role of NSAIDs in the development and resolution of this condition.

Main Methods:

  • Case report of a 20-year-old female marathon runner presenting with diarrhea and bloody stool.
  • Review of medical literature on ischemic colitis and exercise-induced gastrointestinal issues.
  • Clinical assessment and patient history focusing on NSAID use.

Main Results:

  • The patient developed symptoms consistent with ischemic colitis during a marathon.
  • Discontinuation of NSAID use led to complete resolution of symptoms.
  • The patient was able to resume running activities without recurrence.

Conclusions:

  • Ischemic colitis is a plausible diagnosis in endurance athletes presenting with gastrointestinal bleeding.
  • NSAID use is a significant risk factor and should be considered in the management of exercise-induced ischemic colitis.
  • Conservative management, including NSAID cessation, can be effective in resolving symptoms and allowing athletes to return to sport.