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Published on: August 19, 2021
Lymphoma of the cervix
Juanita Parnis1, David J Camilleri, Darko Babic
1Department of Surgery, Mater Dei Hospital, Msida MSD 2090, Malta.
Case Reports in Hematology
|October 24, 2012
Summary
Primary non-Hodgkin
Area of Science:
- Gynecologic Oncology
- Hematology
- Oncology
Background:
- Primary non-Hodgkin's lymphoma of the uterine cervix is an extremely rare clinical diagnosis.
- Postmenopausal bleeding is a common symptom that can mask rare gynecologic malignancies.
Purpose of the Study:
- To report a rare case of primary non-Hodgkin's lymphoma of the uterine cervix.
- To discuss the diagnostic and therapeutic approach for this rare condition.
Main Methods:
- A case study of a 54-year-old woman presenting with postmenopausal bleeding.
- Cervical biopsies and endometrial curettage for histological examination.
- Diagnosis confirmed by CD 20 positive high-grade non-Hodgkin's diffuse large B cell lymphoma.
- Staging workup followed by treatment with R-CHOP chemotherapy and radiotherapy.
Main Results:
- Histological analysis confirmed diffuse large B cell lymphoma.
- The patient was diagnosed with stage IE disease.
- Successful treatment with six cycles of R-CHOP chemotherapy and involved field radiotherapy.
Conclusions:
- Primary cervical lymphoma, though rare, should be considered in cases of persistent postmenopausal bleeding.
- Multimodality treatment including chemotherapy and radiotherapy can be effective for stage IE disease.
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01:16Primary Lymphoid Organs
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01:15Secondary Lymphoid Organs
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01:18Lymphoid Cells and Tissues
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