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Related Concept Videos

Oral Drug Delivery Systems: Introduction01:23

Oral Drug Delivery Systems: Introduction

Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
Drugs in...
Routes of Drug Administration: Enteral01:18

Routes of Drug Administration: Enteral

Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules01:18

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...

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Related Experiment Video

Updated: May 17, 2026

Formation of Dispersible Taohong Siwu Tablets
05:44

Formation of Dispersible Taohong Siwu Tablets

Published on: February 3, 2023

[Galenic forms for oral medication].

Ousseid El Semman1, Agnès Certain, Faouzia Bouziane

  • 1GHI Le Raincy-Montfermeil. oelsemman@ch-montfermeil.fr

Revue De L'Infirmiere
|October 25, 2012
PubMed
Summary

Nurses may need to alter drug formulations for easier patient administration. Careful handling of pharmaceutical forms is essential for safe medication delivery and patient care.

Area of Science:

  • Pharmaceutical Sciences
  • Nursing Practice

Background:

  • Galenic science focuses on drug formulation and excipient use for patient administration.
  • Pharmaceutical forms are designed for various routes, including oral delivery.

Purpose of the Study:

  • To highlight the role of nurses in managing and modifying drug pharmaceutical forms.
  • To emphasize the importance of vigilance when altering medication for patient ease.

Main Methods:

  • Review of pharmaceutical formulation principles.
  • Analysis of nursing responsibilities in medication administration.

Main Results:

  • Nurses encounter situations requiring modification of existing pharmaceutical forms.
  • Altering drug forms necessitates a thorough understanding of formulation science.

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Gavage Strategy for Decoction Formula of Traditional Chinese Medicine in Osteosarcoma Model Mice

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Formation of Dispersible Taohong Siwu Tablets
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Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals
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Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals

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Conclusions:

  • Nurses play a critical role in adapting medication forms for patient compliance.
  • Vigilance and knowledge of Galenic science are crucial for safe medication handling by nurses.