Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atypical Pneumonia

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

Bacterial Phylum Tenericutes

Bacterial Phylum Tenericutes

The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluation of IndiMix JOE with Intype IC-RNA as an Alternative to AgPath-ID for Influenza A Virus Detection in Avian and Bovine Samples.

Pathogens (Basel, Switzerland)·2026

Same author

Imaging diagnosis of Caroli-like disease with concurrent extrahepatic biliary obstruction in a young small-breed dog: case report.

Frontiers in veterinary science·2026

Same author

Material Composition and Implantation Site Affect in vivo Device Degradation Rate.

Research square·2026

Same author

Highly Pathogenic Avian Influenza A(H5N1) Virus RNA in Bovine Semen, California, USA, 2024.

Emerging infectious diseases·2026

Same author

Response to ethical concern regarding "Magnetic resonance imaging features of bilateral multiloculated extraneural ganglion cysts of the occipito-atlanto-axial joint causing hypoglossal nerve paralysis in a dog".

Journal of veterinary internal medicine·2026

Same author

Midgestational injection of highly expanded human CD34+ cells increases lineages of human immune cells and supports thymic development in <i>RAG2-/-IL2RG-/Y</i> SCID pigs.

Frontiers in immunology·2026

Search research articles

Related Experiment Video

Updated: May 17, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Mycoplasmosis in ferrets.

Matti Kiupel¹, Danielle R Desjardins, Ailam Lim

¹Diagnostic Center for Population and Animal Health, Michigan State University, Lansing, MI 48910, USA. kiupel@dcpah.msu.edu

Emerging Infectious Diseases

|October 25, 2012

Summary

This summary is machine-generated.

A novel Mycoplasma species caused a severe respiratory disease in young ferrets, leading to widespread coughing. This finding identifies a new ferret pathogen responsible for significant illness but low mortality.

More Related Videos

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

Related Experiment Videos

Last Updated: May 17, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

Area of Science:

Veterinary Medicine
Microbiology
Animal Health

Background:

A significant outbreak of respiratory illness occurred in young ferrets imported from Canada between 2009 and 2012.
The disease primarily manifested as nonproductive coughing, affecting approximately 95% of nearly 8,000 affected ferrets.

Purpose of the Study:

To identify the causative agent of a novel respiratory disease in ferrets.
To characterize the novel Mycoplasma species and its association with the observed pulmonary pathology.

Main Methods:

Postmortem examinations and histopathology were performed on affected ferrets.
Immunohistochemistry was used to detect Mycoplasma species in lung tissues.
Bronchoalveolar lavage samples were collected for microbial culture and identification.
Nucleic acid sequencing of 16S rDNA and RNA polymerase B genes was employed for molecular identification.

Main Results:

Histopathology revealed bronchointerstitial pneumonia with lymphoid tissue hyperplasia.
Immunohistochemistry showed Mycoplasma bovis antigen presence along bronchiolar borders.
Cultured mycoplasmas were fast-growing and glucose-fermenting.
Sequence analysis indicated the novel species was most similar to Mycoplasma molare and Mycoplasma lagogenitalium, but unidentifiable with current databases.

Conclusions:

A novel Mycoplasma species is causally associated with a newly recognized pulmonary disease in ferrets.
The identified pathogen leads to significant morbidity, primarily characterized by persistent coughing.
Further research is needed to fully characterize and name this novel Mycoplasma species.