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Updated: May 17, 2026
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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
Male lower urinary tract symptoms associated with overactive bladder
1Senior Lecturer in Urology, University of Bristol, Bristol, UK.
Summary
Men with overactive bladder (OAB) storage symptoms should initially use antimuscarinic agents for better treatment response than alpha blockers. Botulinum toxin A is a potential therapy for those refractory to current treatments.
Area of Science:
- Urology
- Pharmacology
Background:
- Lower urinary tract symptoms (LUTS) are common in men.
- Overactive bladder (OAB) significantly impacts quality of life.
Purpose of the Study:
- To evaluate the efficacy of antimuscarinic therapy versus alpha blockade for LUTS in men with OAB.
- To explore alternative treatments for pharmacotherapy-refractory OAB.
Main Methods:
- Comparative analysis of treatment responses.
- Review of emerging evidence for novel therapies.
Main Results:
- Antimuscarinic agents demonstrate superior response rates compared to alpha blockade for OAB storage symptoms.
- Botulinum toxin A shows promise for refractory cases.
Conclusions:
- Initial treatment for men with OAB storage symptoms should prioritize antimuscarinic therapy.
- Botulinum toxin A represents a viable option for treatment-resistant OAB.
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