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A New Ex Vivo Model for the Evaluation of Endoscopic Submucosal Injection Material Performance
Published on: October 19, 2018
Ex vivo comparative study using the Endolifter® as a traction device for enhancing submucosal visualization during
Anthony Yuen Bun Teoh1, Philip Wai Yan Chiu, So Fei Hon
1Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China. anthonyteoh@surgery.cuhk.edu.hk
Surgical Endoscopy
|October 25, 2012
Summary
The Endolifter device significantly improved submucosal visualization during endoscopic submucosal dissection (ESD) procedures. This traction device reduced procedural difficulty and time, potentially aiding ESD in various settings.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic submucosal dissection (ESD) is a complex procedure.
- Submucosal visualization relies on gravity and injection, which can be limiting.
Purpose of the Study:
- To evaluate the Endolifter device's effectiveness in improving submucosal visualization during ESD.
- To assess the impact of the Endolifter on procedural outcomes and difficulty.
Main Methods:
- Prospective ex vivo comparative study of gastric ESD with and without the Endolifter.
- Four experienced endoscopists performed procedures on an ex vivo model.
- Outcomes included submucosal visualization ratio, procedural time, and difficulty ratings.
Main Results:
- The Endolifter group showed a significantly higher submucosal visualization ratio (P = 0.007).
- Procedural and dissection times were reduced with the Endolifter.
- Procedures were rated as less difficult in the Endolifter group (P = 0.033).
Conclusions:
- The Endolifter enhances submucosal visualization and reduces difficulty in gastric ESD.
- This device may facilitate ESD, especially in centers with lower case volumes or for large lesions.