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Updated: May 17, 2026

Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
Published on: June 10, 2022
An interesting finding in a congenital cystic adenomatoid malformation
Katherine Elizabeth Jones1, Ying Teo, Kokila Lakhoo
1Department of West Wing, Children's Hospital, John Radcliffe Hospital, Oxford, UK. jonesyk100@yahoo.co.uk
Abstract:
Here we describe a case of antenatally diagnosed congenital cystic adenomatoid malformation. Due to increasing cyst size and fetal hydrops an antenatal drain was inserted. The lesion was excised surgically soon after birth due to significant respiratory distress. During histological assessment an area of squamous metaplasia was found within the cyst wall. This developed as a result of the drain placement. At 4-year follow-up the child remains well and has experienced no long-term respiratory sequalae.
