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Multiparametric statistical correlations between paranasal sinus anatomic variations and chronic rhinosinusitis
1ENT DEPT San Luigi Gonzaga, University Hospital, Turin, Italy. gl.fadda@libero.it
Summary
Anatomic variations in the paranasal region are common in chronic sinusitis patients. Specific variations like septal deviation and concha bullosa significantly correlate with sinus mucosal disease, highlighting the need for CT evaluation.
Area of Science:
- Otolaryngology
- Radiology
- Anatomy
Background:
- Chronic rhinosinusitis (CRS) affects many patients, often necessitating surgical intervention.
- Advances in functional endoscopic sinus surgery (FESS) and computed tomography (CT) have spurred interest in paranasal anatomy.
- Anatomical variations are frequently observed in patients with CRS.
Purpose of the Study:
- To investigate the incidence of lateral nasal wall anatomical variations in patients with refractory CRS.
- To determine the correlation between these anatomical variations and paranasal sinus disease.
- To identify specific variations associated with increased risk of rhinosinusitis.
Main Methods:
- Retrospective analysis of CT scans from 200 patients with persistent rhinosinusitis symptoms.
- Detailed examination of lateral nasal wall anatomy and paranasal sinus disease.
- Statistical analysis using Fisher's exact test to assess correlations.
Main Results:
- 70% of patients exhibited anatomical variations, with 87% having common variations.
- Maxillary and ethmoid sinuses were most frequently involved.
- Significant association found between common variations (septal deviation, concha bullosa, Haller cell, etc.) and sinus mucosal disease (p < 0.05).
Conclusions:
- Certain anatomical variations of the lateral nasal wall are significantly associated with the presence and severity of paranasal sinus mucosal disease.
- These findings underscore the importance of meticulous CT evaluation in patients with persistent CRS to identify at-risk individuals.
- Identifying anatomical variations can aid in personalized treatment strategies for chronic rhinosinusitis.
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