The many faces of minimal change nephrotic syndrome: an overview and case study

Idiopathic nephrotic syndrome is the most common form of nephrotic syndrome in the pediatric population. Three major histopathological findings have been identified. The most common is that of minimal change nephrotic syndrome. Most of these cases respond well to oral steroids and achieve long-term remission. For those that become steroid dependent, the clinical course can be quite difficult. The case study included demonstrates some of the difficulties that can be encountered and questions that still exist with management of this diagnosis.