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Updated: May 17, 2026

Local Hyperthermia for Warts Treatment

Local Hyperthermia for Warts Treatment

Published on: November 8, 2024

Giant condyloma acuminatum quickly growing: case report.

R Patti¹, P Aiello, G L Angelo

¹Department of Surgery and Oncology Sciences, General Surgery Unit, University of Study of Palermo, Italy.

Il Giornale Di Chirurgia

|October 26, 2012

Summary

Giant Condyloma Acuminatum (GCA), a rare perianal tumor, can be effectively treated with wide surgical excision and skin grafting. This approach minimizes recurrence risk for this Human Papilloma Virus-associated condition.

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Last Updated: May 17, 2026

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Published on: November 8, 2024

Area of Science:

Dermatology
Oncology
Surgical Gastroenterology

Background:

Giant Condyloma Acuminatum (GCA) is a rare, slow-growing tumor associated with Human Papilloma Virus (HPV) types 6 and 11.
GCA presents with a benign histologic appearance but has a high propensity for local invasion and recurrence.
There is a considerable risk of neoplastic transformation into squamous cell carcinoma within approximately 5 years.

Observation:

Perianal GCA is rare, leading to a lack of consensus on optimal treatment strategies.
A case report details the treatment of a 28-year-old HIV-negative male with a 4-year history of rapidly growing perianal GCA.
The patient underwent full-thickness local excision with a 0.7 cm margin and immediate thigh skin grafting.

Findings:

Surgical management involved complete tumor excision and immediate reconstruction with skin grafting.
Postoperative measures included dietary modifications and loperamide to prevent fecal contamination.
At two years of follow-up, no recurrence of the perianal GCA was observed.

Implications:

Full-thickness surgical excision with immediate skin grafting is an effective treatment for perianal GCA.
This surgical approach can significantly minimize the risk of disease recurrence.
Regular follow-up is crucial for managing GCA and detecting any potential recurrence.