Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Dipeptidyl Peptidase 4 Inhibitors

Dipeptidyl Peptidase 4 Inhibitors

Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a significant...

SBAR II: Application of SBAR

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...

Diabetes Mellitus: Introduction

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are typically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Psychosocial challenges and enrichment in post-9/11 Veteran reintegration: A multidimensional exploratory analysis.

Military psychology : the official journal of the Division of Military Psychology, American Psychological Association·2026

Same author

Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs.

Frontiers in veterinary science·2025

Same author

Regional Medical Operations Coordinating Centers Promote Readiness for Daily Trauma Care and Mass Casualty Incidents.

Journal of the American College of Surgeons·2025

Same author

Retrospective analysis of the effects of hypocalcemia in severely injured trauma patients.

Injury·2024

Same author

Risk factors for massive transfusion in obstetrical hemorrhage and consideration of a whole blood program.

Transfusion·2023

Same author

Transfusion-related cost comparison of trauma patients receiving whole blood versus component therapy.

The journal of trauma and acute care surgery·2023

Search research articles

Related Experiment Video

Updated: May 17, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Improving glycemic control with the adjunct use of a data management software program.

Charles C Reed¹, Jacqueline M Richa, Andrea E Berndt

¹University Health System, Medical Drive, San Antonio, TX 78229, USA. charles.reed@uhs-sa.com

AACN Advanced Critical Care

|October 26, 2012

Summary

Implementing real-time blood glucose (BG) reports improved tight glucose control (TGC) programs. This data management software enhanced BG level monitoring and patient outcomes in a surgical trauma ICU.

Related Experiment Videos

Last Updated: May 17, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Area of Science:

Critical Care Medicine
Endocrinology
Health Informatics

Background:

Published studies support tight glucose control (TGC) for improved patient outcomes and reduced mortality.
Measuring TGC program efficiency is challenging due to data capture, access, and analysis limitations.
Real-time blood glucose (BG) results reports were hypothesized to improve TGC program efficacy.

Purpose of the Study:

To evaluate the impact of real-time BG data reports on the efficacy of a TGC program.
To assess changes in BG levels and control within a surgical trauma intensive care unit.

Main Methods:

Retrospective review of BG data over 12 months in a surgical trauma ICU.
Utilized a unit-specific insulin algorithm and compared BG values before and after data management software implementation.
Daily and weekly reports of real-time BG data were used to monitor the TGC program.

Main Results:

Analyzed 70,616 BG values from 1044 patients.
Mean BG levels decreased from 121 mg/dL to 112 mg/dL (P < .001).
Percentage of BG values within the target range (80-110 mg/dL) increased from 38.9% to 50.4% (P < .001).
Percentage of BG values < 70 mg/dL increased from 2.7% to 3.4% (P < .001), with no change in severe hypoglycemia (≤ 40 mg/dL).

Conclusions:

Access to real-time aggregated BG data reports via data management software significantly improved TGC program efficacy.
The software facilitated better monitoring and control of glucose levels in critically ill patients.
Real-time data access is crucial for optimizing TGC program performance in intensive care settings.