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Updated: May 17, 2026

Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
[Human intestinal spirochetosis: clinical series and literature review]
Carlo Lozano1, Leonardo Arellano, Pamela Yaquich
1Servicio de Anatomía Patológica, Hospital del Salvador, Santiago, Chile.
Introduction:
Human intestinal spirochetosis (HIE) is defined as colonization by spirochetes of the large intestine. Is associated with chronic diarrhea. The incidence and prevalence ranges from 0.4% to 12%.
Objective:
To determine the prevalence of HIE in the Salvador's Hospital, between 2003 and 2008 in patients with a history of chronic diarrhea and without abnormalities in colonoscopy, in 2 separate groups: patients with and without a history of HIV infection.
Material And Methods:
Retrospective morphology evaluation of the large bowel endoscopic biopsies to the selected groups.
Results:
We reviewed 115 biopsies, 98 were from HIV-negative and 17 HIV from positive patients. Two cases of intestinal spirochetosis were detected, both HIV negative, with a prevalence of 1.7%.
Comment:
The prevalence of HIE is similar to that reported in Western countries. Population studies are needed to determine the real epidemiological impact in our environment.
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