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Related Concept Videos

Eukaryotic Compartmentalizations01:46

Eukaryotic Compartmentalizations

One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...
Eukaryotic Compartmentalization01:37

Eukaryotic Compartmentalization

One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...
Eukaryotic Compartmentalization01:46

Eukaryotic Compartmentalization

One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...
Overview of Secretory Vesicles01:33

Overview of Secretory Vesicles

Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
Yeast Signaling01:28

Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
The Inner Mitochondrial Membrane01:28

The Inner Mitochondrial Membrane

The inner mitochondrial membrane is the primary site of ATP synthesis. The inner membrane domain that forms a smooth layer adjacent to the outer membrane is called the inner boundary membrane. This domain contains membrane transporters that drive metabolites in and out of the mitochondria.  In contrast, the inner membrane network that invaginates into the matrix space is called the cristae membrane. This domain accounts for principle mitochondrial function as it accommodates the protein...

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Assessment of Submitochondrial Protein Localization in Budding Yeast Saccharomyces cerevisiae
08:55

Assessment of Submitochondrial Protein Localization in Budding Yeast Saccharomyces cerevisiae

Published on: July 19, 2021

Microcompartments within the yeast plasma membrane.

Hans Merzendorfer1, Jürgen J Heinisch

  • 1Department of Biology/Chemistry, University of Osnabrück, Animal Physiology, Barbarastr. 11, 49076 Osnabrück, Germany. merzendorfer@biologie.uni-osnabrueck.de

Biological Chemistry
|October 26, 2012
PubMed
Summary
This summary is machine-generated.

Eukaryotic cell physiology relies on microcompartmentation, the dynamic interaction of molecules within suborganellar spaces. This review explores yeast plasma membrane microcompartments crucial for cell division and survival.

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Area of Science:

  • Cell Biology
  • Molecular Biology
  • Biochemistry

Background:

  • The classical view of eukaryotic cell organelles is being expanded by the concept of microcompartmentation, involving dynamic molecular interactions at a suborganellar level.
  • The yeast Saccharomyces cerevisiae, with its well-characterized plasma membrane compartments (MCs), serves as a model for studying these dynamic structures.
  • Specific MCs, including eisosomes and chitin-synthesizing complexes, play vital roles in cellular processes.

Purpose of the Study:

  • To review and compare specialized microcompartments within the yeast plasma membrane.
  • To highlight the role of these microcompartments in ensuring proper cell division.
  • To emphasize the significance of microcompartmentation for eukaryotic cell survival and proliferation.

Main Methods:

  • Comparative analysis of existing research on yeast plasma membrane substructures.
  • Focus on eisosomes, cell wall integrity-sensing units, and chitin-synthesizing complexes.
  • Integration of genetic, biochemical, and microscopic study findings.

Main Results:

  • Yeast bud neck microcompartments are specialized structures essential for cell division.
  • Plasma membrane substructures like eisosomes and chitin-synthesizing complexes contribute to cell integrity and division.
  • Microcompartmentation is critical for the regulation of mitosis in eukaryotic cells.

Conclusions:

  • Microcompartmentation extends the classical organelle concept and is vital for cell physiology.
  • Specialized yeast plasma membrane microcompartments are crucial for successful cell division.
  • Understanding these dynamic structures is essential for comprehending the survival and proliferation of all eukaryotic cells.