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[Accuracy of multislice CT in restaging patients with non-small cell lung carcinoma after neoadjuvant chemotherapy
Maria Antonietta Mazzei1, Susanna Guerrini, Eugenio Annibale Genovese
1Dipartimento di Patologia, Universita di Siena. mariaantonietta.mazzei@unisi.it
Abstract:
The aim of this study was to assess diagnostic accuracy of multislice CT in restaging patients with N2 non-small cell lung carcinoma after neoadjuvant chemotherapy, using a multiparametric approach as compared with traditional size-based radiological criteria. All patients staged as N2 at histologic examination after neoadjuvant chemotherapy were correctly staged with multislice CT (sensitivity, specificity, positive and negative predictive value, and accuracy were 100%, 80%, 85%, 100% and 93,7% respectively, vs 34%, 60%, 34%, 60% and 50% using size-based criteria), suggesting that a multiparametric approach results in improved diagnostic accuracy.