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Updated: May 17, 2026

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
A coumarin-Meldrum's acid conjugate based chemodosimetric probe for cyanide
Hongda Li1, Zhi Wen, Longyi Jin
1Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Yanbian University, Ministry of Education, Yanji, Jilin, China.
Abstract:
A highly reactive and selective chemodosimetric probe for cyanide was synthesized based on alkylidene Meldrum's acid as a novel cyanide reaction site. A theoretical study was conducted to rationalize the high reactivity and the photophysical properties of probe 1 and the 1-CN adduct.
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