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Updated: May 17, 2026

Fabrication of Decellularized Cartilage-derived Matrix Scaffolds
Published on: January 7, 2019
The use of acellular dermal matrices in chest wall reconstruction
Neel R Sodha1, Saïd C Azoury, Christopher Sciortino
1Baltimore, Md. From the Department of Surgery, Division of Thoracic Surgery, and the Department of Plastic and Reconstructive Surgery, The Johns Hopkins Medical Institutions.
Abstract:
Surgeons are faced with increasingly complex and larger chest wall defects as a result of a variety of pathologies, the majority of which are oncologic. Skeletal reconstruction of these resulting defects and subsequent soft-tissue coverage remain a challenge for thoracic and plastic and reconstructive surgeons. A variety of techniques and grafts have been utilized to support the thoracic cage. This review focuses on the use of acellular dermal matrices in thoracic skeletal reconstruction, with a focus on the indications, published data, and surgical techniques for utilizing acellular dermal matrices in chest wall reconstruction.

