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Related Experiment Video

Updated: May 17, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

Finding a single lanthanide ion through upconversion.

Xiaoyong Huang¹, Xiaogang Liu

¹Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry

|October 26, 2012

Summary

Researchers achieved optical detection of single lanthanide ions using a two-step upconversion process in YAG:Pr(3+) nanocrystals. This breakthrough enables highly sensitive ion detection for various applications.

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Area of Science:

Nanotechnology
Materials Science
Spectroscopy

Background:

Lanthanide ions are crucial in various applications, but their detection at the single-ion level remains challenging.
Optical detection methods offer high sensitivity but require advanced techniques for single-ion resolution.

Purpose of the Study:

To develop a method for the optical detection of single lanthanide ions.
To demonstrate the feasibility of using nanocrystals for ultrasensitive ion detection.

Main Methods:

Utilized YAG:Pr(3+) nanocrystals as the host material.
Implemented a two-step upconversion process for signal amplification.
Employed optical spectroscopy to detect individual lanthanide ions.

Main Results:

Successfully achieved optical detection of a single lanthanide ion.
Demonstrated the effectiveness of the two-step upconversion process in YAG:Pr(3+) nanocrystals.
Showcased the potential for ultrasensitive ion detection.

Conclusions:

The developed method enables the optical detection of single lanthanide ions.
YAG:Pr(3+) nanocrystals are a promising platform for ultrasensitive ion detection.
This technique opens new avenues for research in nanosensing and materials science.