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[Control of myocardial ischemia in patients with effort angina and polyvascular atherosclerotic involvement]

E V Saiutina, V V Chigineva, E A Zolozova

    Kardiologiia
    |October 27, 2012
    PubMed

    Insights

    Effective treatment for ischemic heart disease involves using cardioselective beta-blockers to manage arterial pressure and heart rate. Additional medications like calcium antagonists and ACE inhibitors can further control myocardial ischemia in daily life.

    Area of Science:

    • Cardiology
    • Vascular Medicine
    • Pharmacology

    Background:

    • Ischemic heart disease (IHD) often coexists with peripheral artery atherosclerosis.
    • Managing cardiovascular risk factors is crucial in IHD patients.

    Purpose of the Study:

    • To evaluate a therapeutic strategy for IHD patients with peripheral artery disease.
    • To assess the control of myocardial ischemia and heart rate in daily life.

    Main Methods:

    • Therapy included cardioselective beta-blockers as the primary choice.
    • Calcium antagonists and angiotensin-converting enzyme inhibitors were added as needed.
    • Focus on maintaining target arterial pressure and heart rate levels.

    Main Results:

    • The described therapeutic approach successfully controlled myocardial ischemia.
    • Target heart rate levels were effectively maintained under everyday conditions.
    • Arterial pressure management was achieved in patients with IHD and peripheral artery atherosclerosis.

    Conclusions:

    • Cardioselective beta-blockers, with potential additions, are effective for managing IHD.
    • This strategy aids in controlling myocardial ischemia and heart rate in patients with concurrent peripheral artery disease.
    • Achieving target blood pressure and heart rate is feasible in daily life for this patient group.

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