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Related Concept Videos

Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...

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Mechanisms Involved in the Enhanced Susceptibility of Senescent Rats to the Hepatocarcinogenic Effect of Peroxisome Proliferators: Role of Peroxisome Proliferator-Activated Receptor alpha (PPAR), Cell Proliferation and Oxidative Stress.

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Characterizing Modulators of Protease-Activated Receptors with a Calcium Mobilization Assay Using a Plate Reader
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PPARs: history and advances.

Jihan Youssef1, Mostafa Z Badr

  • 1University of Missouri-Kansas City, Kansas City, MO, USA.

Methods in Molecular Biology (Clifton, N.J.)
|October 27, 2012
PubMed
Summary

Peroxisome proliferator-activated receptors (PPARs) are crucial for regulating various bodily functions. Researching PPARs aids in understanding and treating diseases like diabetes and cancer.

Area of Science:

  • Molecular biology
  • Endocrinology
  • Pharmacology

Background:

  • Peroxisome proliferator-activated receptors (PPARs) belong to the steroid hormone receptor superfamily.
  • Three subtypes exist: PPARα, PPARβ/δ, and PPARγ, with distinct tissue distribution and ligand specificities.

Observation:

  • PPARs play roles in diverse physiological processes.
  • They are implicated in the development and treatment of diseases including diabetes, inflammation, and cancer.

Findings:

  • Ongoing research aims to uncover novel PPAR functions and mechanisms.
  • Development of safer and more effective PPAR modulators is a key focus.

Implications:

  • Understanding PPARs can lead to new therapeutic strategies for metabolic and oncological diseases.

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  • This research volume provides essential experimental protocols for studying PPARs.