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Updated: May 17, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrial fibrillation in a tertiary care institute - a prospective study
1Indira Gandhi Medical College, Shimla, India. rajeevbhardwaj_dr@yahoo.com
Insights
In North India, rheumatic heart disease is the primary cause of atrial fibrillation (AF), affecting over 60% of patients. Hypertensive heart disease and COPD are also significant contributors to AF.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Atrial fibrillation (AF) is a prevalent cardiac arrhythmia.
- Common causes in Western countries include hypertensive heart disease, dilated cardiomyopathy, and coronary heart disease.
- Rheumatic heart disease (RHD) remains a significant health issue in India.
Purpose of the Study:
- To investigate the contribution of rheumatic heart disease to atrial fibrillation in North India.
- To identify the leading causes of atrial fibrillation in a rural Indian population.
Main Methods:
- A cohort of 137 consecutive patients diagnosed with atrial fibrillation was studied.
- Echocardiography was performed on all patients to determine the underlying cause of AF.
- Demographic data, including age and gender, were collected.
Main Results:
- Rheumatic heart disease was identified as the most common cause of atrial fibrillation, accounting for 61.31% of cases (84 patients).
- Hypertensive heart disease and chronic obstructive pulmonary disease (COPD) were the next most frequent causes, each found in 10.2% of patients (14 patients each).
- The mean age of the patients was 51.24 years, with a higher prevalence in females (55.47%).
Conclusions:
- Rheumatic heart disease is the predominant cause of atrial fibrillation in the studied rural North Indian population, responsible for over 60% of cases.
- Hypertensive heart disease and COPD are the subsequent significant etiological factors for AF in this demographic.
- Understanding regional etiological variations is crucial for targeted prevention and management strategies for atrial fibrillation.
Objective:
Atrial fibrillation is the commonest sustained arrhythmia. In western countries the common causes of atrial fibrillation are hypertensive heart disease, dilated cardiomyopathy, and coronary heart disease. Rheumatic heart disease being still common in India, we studied its contribution to atrial fibrillation.
Material And Methods:
137 consecutive patients of atrial fibrillation coming to our hospital were subjected to echocardiography to determine the cause.
Results:
Out of 137 patients with atrial fibrillation, 76 were female (55.47%) and 61 were male (44.43%). Mean age was 51.24±15.36 years. Commonest cause of AF was rheumatic heart disease found in 84 (61.31%) patients. Next common causes were hypertensive heart disease in 14 (10.2%) patients and chronic obstructive pulmonary disease (COPD) in 14 (10.2%) patients. Mean left atrial size was 47.8±12.25mm.
Conclusion:
In our study of patients coming from a rural back ground of North India, more than 60% patients of AF are due to RHD. Hypertensive heart disease and COPD are the next common causes.
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