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Related Experiment Videos

Implantable rate-responsive counterpulsation assist system.

C M Li1, A Hill, M Colson

  • 1Division of Cardiovascular and Thoracic Surgery, McGill University, Montreal, Canada.

The Annals of Thoracic Surgery
|March 1, 1990
PubMed
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This study introduces an implantable cardiac assist system powered by skeletal muscle, demonstrating effective counterpulsation and potential for continuous cardiac support in animal models.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Implantable Medical Devices

Background:

  • Skeletal muscle offers a potential energy source for cardiac assistance.
  • Existing cardiac assist devices face limitations in long-term support.
  • Novel approaches are needed for effective and adaptable cardiac support systems.

Purpose of the Study:

  • To evaluate an implantable counterpulsation assist system powered by skeletal muscle.
  • To assess the system's performance in an acute in vivo animal model.
  • To determine the feasibility of using skeletal muscle for cardiac assistance.

Main Methods:

  • Developed a dual-chambered, extraaortic counter-pulsation pump powered by the left latissimus dorsi muscle.
  • Utilized a novel implantable stimulator for synchronized muscle contraction and automatic timing adjustments.

Related Experiment Videos

  • Tested the system in twelve dogs, inducing changes in heart rate and arrhythmias.

    • Main Results:

    • The system effectively augmented diastolic pressure by 69% and reduced systolic pressure by 11%.
    • The stimulator successfully adjusted to changing heart rates, maintaining optimal counterpulsation.
    • The system demonstrated safety features, including automatic shutdown during induced ventricular tachycardia.

    Conclusions:

    • The implantable counterpulsation assist system provides effective cardiac support.
    • Skeletal muscle power is a viable option for cardiac assistance.
    • The system shows potential for continuous cardiac support and adaptability to physiological changes.