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Updated: May 17, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Medical versus medical and surgical treatment for brucella endocarditis
Maryam Keshtkar-Jahromi1, Seyed-Mostafa Razavi, Sharareh Gholamin
1Union Memorial Hospital, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
Abstract:
This review was undertaken to determine the role of surgery in the treatment of brucella endocarditis. All English and French articles reporting brucella endocarditis (1966 to 2011) in PubMed, Google, and Scopus were reviewed. In all, 308 cases were identified, and linear and logistic regression was performed. Surgery improved outcomes by decreasing mortality from 32.7% in the medical treatment only group to 6.7% in the combined surgical and medical treatment group (p<0.001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients.
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