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Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Anaortic, total-arterial, off-pump coronary artery bypass surgery: why bother?
J J B Edelman1, A G Sherrah, M K Wilson
1Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia.
Insights
Anaortic, total-arterial off-pump coronary artery bypass (OPCAB) grafting offers surgical revascularization benefits with stroke rates comparable to percutaneous coronary intervention (PCI). This review highlights the advantages of the anaortic OPCAB technique.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Coronary artery bypass grafting (CABG) is standard for multi-vessel coronary disease.
- Peri-operative stroke risk with CABG exceeds that of percutaneous coronary intervention (PCI).
Purpose of the Study:
- To review the benefits of anaortic, total-arterial off-pump coronary artery bypass (OPCAB) grafting.
- To address concerns regarding off-pump techniques potentially influenced by aortic manipulation in some trials.
Main Methods:
- Review of existing literature and surgical techniques.
- Comparison of anaortic OPCAB with conventional CABG and PCI, focusing on stroke rates and surgical advantages.
Main Results:
- Anaortic, total-arterial OPCAB grafting provides surgical revascularization advantages.
- This technique achieves stroke rates equivalent to PCI, mitigating a key concern of traditional CABG.
Conclusions:
- The anaortic, total-arterial OPCAB technique is a viable and increasingly adopted alternative.
- It offers comparable stroke risk to PCI while retaining the benefits of surgical revascularization.
Abstract:
Coronary artery bypass grafting (CABG) remains the standard of care for multi-vessel coronary disease. However, the increased rate of peri-operative stroke reported after surgery compared to percutaneous coronary intervention (PCI) remains of concern. Anaortic, total-arterial, off-pump coronary artery bypass (OPCAB) grafting is a technique that offers the main advantages of surgical revascularisation with a rate of stroke that is equivalent to that of PCI. Some recent trials comparing conventional on-pump CABG with OPCAB have questioned the efficacy of the off-pump technique - these are most often performed with manipulation of the ascending aorta. We review the potential benefits of the anaortic, total-arterial OPCAB technique to explain why it is being employed by an increasing number of surgeons.
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