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Related Concept Videos

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

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Updated: May 17, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
10:37

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

Published on: November 30, 2016

Food patch testing for irritable bowel syndrome.

Michael B Stierstorfer1, Christopher T Sha, Marvin Sasson

  • 1East Penn Dermatology PC, North Wales, Pennsylvania 19454, USA. mstierstorfer@eastpennderm.com

Journal of the American Academy of Dermatology
|October 30, 2012
PubMed
Summary
This summary is machine-generated.

Skin patch testing may identify food allergens contributing to irritable bowel syndrome (IBS) symptoms. Avoiding identified allergens led to symptom improvement in some patients, suggesting a role for allergic contact enteritis in IBS.

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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

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Last Updated: May 17, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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Published on: November 30, 2016

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Area of Science:

  • Gastroenterology
  • Allergology
  • Immunology

Background:

  • Irritable bowel syndrome (IBS) is increasingly linked to low-grade gastrointestinal inflammation, challenging its traditional functional disorder classification.
  • Inflammation may disrupt gastrointestinal motility, playing a key role in IBS pathogenesis.
  • Allergic reactions to foods and additives, known to cause skin conditions, are hypothesized to trigger similar gastrointestinal responses.

Purpose of the Study:

  • To investigate the utility of skin patch testing in identifying food allergens responsible for IBS symptoms.
  • To determine if patch testing can guide dietary interventions for IBS management.

Main Methods:

  • Skin patch testing was conducted on individuals with IBS symptoms using common allergenic foods and food additives.
  • Patch test results guided personalized avoidance diets to assess symptom alleviation.

Main Results:

  • Over half of the participants (30/51) exhibited positive or doubtful patch test reactions.
  • A significant portion of participants (14/51) reported symptom improvement after avoiding identified food allergens.

Conclusions:

  • Allergic contact enteritis to ingested foods or food additives may be a contributing factor to IBS.
  • Skin patch testing shows promise as a diagnostic tool for identifying specific food triggers in IBS patients.