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Trazodone-induced palinopsia.

M S Hughes¹, S Lessell

¹Department of Ophthalmology, Harvard Medical School, Boston, MA.

Archives of Ophthalmology (Chicago, Ill. : 1960)

|March 1, 1990

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Palinopsia, a visual disturbance, can be an isolated side effect of trazodone hydrochloride, an antidepressant. This visual symptom is dose-dependent and resolves upon adjusting or stopping the medication.

Area of Science:

Neuroscience
Ophthalmology
Pharmacology

Background:

Palinopsia is typically associated with structural brain lesions affecting visual processing areas.
It often presents with other neurological or visual deficits.

Observation:

Three patients presented with palinopsia as their sole symptom.
These patients were undergoing treatment with trazodone hydrochloride for depression.

Findings:

The palinopsia experienced by these patients was directly linked to their trazodone dosage.
Reducing or discontinuing trazodone therapy led to the resolution of palinopsia.

Implications:

This suggests trazodone hydrochloride can induce palinopsia as an isolated adverse effect.

Related Experiment Videos

Clinicians should consider trazodone-induced palinopsia in patients presenting with this visual disturbance.

Dosage adjustment or discontinuation of trazodone may effectively manage this side effect.