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Published on: April 17, 2026
Solid pseudopapillary neoplasm of the pancreas
Donna Cummins1, Margaret Sheehan, John Bruzzi
1Department of Emergency Medicine, Mater Misericordiae University Hospital, Dublin, Ireland. donnacummins@gmail.com
Solid pseudopapillary neoplasms (SPNs) are rare pancreatic tumors. This case highlights an incidentally discovered SPN in an older female, successfully treated with surgical resection.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Solid pseudopapillary neoplasms (SPNs) are rare pancreatic tumors, typically affecting young females.
- They are often asymptomatic and indolent, growing to large sizes before detection.
Observation:
- A 59-year-old female presented with a wheeze, unrelated to an incidentally discovered 10 cm pancreatic mass on CT scan.
- The mass was well-circumscribed and located adjacent to the pancreatic tail.
Findings:
- Immunohistochemical markers confirmed the diagnosis of a solid pseudopapillary neoplasm.
- Surgical resection was curative, with no evidence of metastasis at presentation.
Implications:
- This case expands the known demographic for SPNs, presenting in an older female.
- Highlights the importance of cross-sectional imaging in identifying incidental pancreatic findings.
- Demonstrates the efficacy of surgical resection for curative treatment of SPNs.
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