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A preliminary study of protein thiols and serum cholinesterase in assisted reproduction
Krishnananda Prabhu1, Pratap Kumar, Muralidhar Pai
1Department of Biochemistry, Kasturba Medical College, Manipal, India.
In this study we sought to investigate the levels of serum protein thiols and cholinesterase levels before and after intrauterine insemination (IUI).We observed 68% patients showed a decrease in protein thiols and 63% showed a decrease in serum cholinesterase levels after insemination as compared to their respective pre procedure levels. The fall in thiols was statistically significant (p=0.021) indicating there is increased oxidative stress after the procedure. However, we could not comment on any reason for the fall in cholinesterase. Whether the changes in above parameters may have some implication on the overall success rate of IUI is yet to be ascertained.
In this study we sought to investigate the levels of serum protein thiols and cholinesterase levels before and after intrauterine insemination (IUI).We observed 68% patients showed a decrease in protein thiols and 63% showed a decrease in serum cholinesterase levels after insemination as compared to their respective pre procedure levels. The fall in thiols was statistically significant (p=0.021) indicating there is increased oxidative stress after the procedure. However, we could not comment on any reason for the fall in cholinesterase. Whether the changes in above parameters may have some implication on the overall success rate of IUI is yet to be ascertained.
