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Pattern-based Search of Epigenomic Data Using GeNemo
06:38

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Published on: October 8, 2017

An efficient approach to mining maximal contiguous frequent patterns from large DNA sequence databases.

Md Rezaul Karim1, Md Mamunur Rashid, Byeong-Soo Jeong

  • 1Department of Computer Engineering, College of Electronics and Information, Kyung Hee University, Yongin 446-701, Korea.

Genomics & Informatics
|October 30, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces an efficient method for discovering long, frequent patterns in DNA sequences without needing to pre-specify their length. The approach is memory-efficient and effective for large biological datasets.

Keywords:
DNA sequencemaximal contiguous frequent patternpattern miningsuffix tree

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Discovering patterns in DNA sequences is crucial for understanding gene function and structure.
  • Maximal contiguous frequent patterns are valuable for identifying common characteristics in related DNA sequences.
  • Existing algorithms often struggle with long sequences or require length pre-specification, limiting their utility.

Purpose of the Study:

  • To develop an efficient algorithm for mining maximal contiguous frequent patterns from large DNA sequence datasets.
  • To address the challenge of finding longer DNA patterns without prior length constraints.
  • To improve the efficiency of pattern discovery in bioinformatics.

Main Methods:

  • Proposed an efficient approach for mining maximal contiguous frequent patterns.
  • Focused on handling large DNA sequence datasets.
  • Evaluated the method's performance in terms of time and memory efficiency.

Main Results:

  • The proposed approach successfully mines maximal contiguous frequent patterns.
  • Demonstrated memory efficiency in handling large datasets.
  • Achieved reasonable mining times for complex DNA sequence analysis.

Conclusions:

  • The developed method offers an efficient solution for identifying significant DNA sequence patterns.
  • This approach overcomes limitations of existing algorithms by not requiring sequence length pre-specification.
  • The findings contribute to advancing pattern discovery in bioinformatics and computational biology.