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Updated: May 17, 2026

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Published on: October 10, 2020
Investigate the Role of Glutathione S Transferase (GST) Polymorphism in Development of Hypertension in UAE Population
Kosar Hussain1, Neveen Salah, Sahar Hussain
1Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
Background:
GST is a family of enzymes that are important in protection of the body against oxidative stress.
Objectives:
Investigate the association between GSTT1 and GSTM1 polymorphism and hypertension.
Materials And Methods:
GSTT1 and GSTM1 genotypes were detected by PCR. The fragments were then analyzed by agarose gel electrophoresis.
Results:
There is no significant association between GSTT1 & GSTM1 polymorphism and hypertension (OR = 2.4, P > 0.05 and OR = 1.6, P > 0.05)
Conclusions:
GSTT1 & GSTM1 polymorphism can be considered a risk factor for hypertension.
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