A common problem for neonatal intensive care units: late preterm infants, a prospective study with term controls in a

Istemi Han Celik1, Gamze Demirel, Fuat Emre Canpolat

  • 1Division of Neonatology, Neonatal Intensive Care Unit, Mersin Maternal and Child Health Hospital, Mersin, Turkey. istemihancelik@gmail.com

Insights

Late preterm infants face higher risks for medical complications and poorer outcomes compared to term infants. Close monitoring and preventive strategies are crucial for these vulnerable newborns after birth.

Area of Science:

  • Neonatal Medicine
  • Pediatrics
  • Public Health

Background:

  • Late preterm infants (34-36 weeks gestation) exhibit physiological and metabolic immaturity.
  • These infants have increased risks for respiratory distress, hypoglycemia, hyperbilirubinemia, sepsis, feeding difficulties, and neurodevelopmental issues.
  • The incidence of late preterm birth is rising globally.

Purpose of the Study:

  • To evaluate the clinical and demographic characteristics of late preterm infants.
  • To assess short-term outcomes and clinical courses of late preterm infants admitted to the NICU.
  • To compare the morbidity and mortality rates of late preterm infants with those of term infants.

Main Methods:

  • Retrospective analysis of data from 605 late preterm and 1477 term infants admitted to a NICU over a 1-year period (June 2010-May 2011).
  • Comparison of admission diagnoses, hospitalization duration, mortality, and rehospitalization rates between the two groups.
  • Calculation of incidence rates based on total deliveries.

Main Results:

  • Late preterm infants represented 30% of NICU admissions, with a mean gestational age of 35 1/7 weeks and birth weight of 2352g.
  • Higher rates of respiratory distress (46.5%), low birth weight (17.5%), jaundice (13.7%), and feeding difficulties (13.1%) were observed in late preterm infants.
  • Mortality (2.1%) and rehospitalization (4.4%) rates were significantly higher in late preterm infants compared to term infants (p < 0.001).

Conclusions:

  • Late preterm infants experience significantly higher morbidity and mortality rates than term infants.
  • Increased vigilance and targeted preventive strategies are essential for managing late preterm infants post-birth.
  • Further research into developing effective preventive measures for late preterm infant complications is warranted.

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