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Updated: May 17, 2026

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Progress in emerging therapies for advanced prostate cancer
1Service d'Oncologie Médicale, Hôpital Européen Georges Pompidou, Université Paris Descartes, Paris 5, Paris, France. stephane.oudard@egp.aphp.fr
Cancer Treatment Reviews
|October 31, 2012
Summary
New therapies are emerging for advanced prostate cancer, including hormone-sensitive and castration-resistant stages. Approved agents and those in phase III trials offer new treatment options for patients.
Area of Science:
- Oncology
- Urology
- Pharmacology
Background:
- Prostate cancer treatment is evolving with new therapeutic options.
- Extensive research is identifying novel agents for advanced disease stages.
Purpose of the Study:
- To review emerging therapies for advanced prostate cancer.
- Focus on agents approved in the USA and EU or in phase III trials.
Main Methods:
- Literature review of recent advancements in prostate cancer therapy.
- Emphasis on approved drugs and late-stage clinical studies.
Main Results:
- Degarelix approved for hormone-sensitive prostate cancer.
- Sipuleucel-T approved in the USA for pre-docetaxel treatment.
- Cabazitaxel, abiraterone acetate, and enzalutamide approved for castration-resistant prostate cancer.
- Denosumab approved for skeletal-related events in bone metastases.
- Radium-223 chloride shows promise in phase III trials.
Conclusions:
- Several new therapies have been approved for various stages of prostate cancer.
- These agents expand treatment options for advanced prostate cancer.
- Ongoing clinical studies suggest continued progress in prostate cancer management.
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