Prevalence of coronary artery disease before valvular surgery in patients with rheumatic valvular disease

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Enver Atalar1, Hikmet Yorgun, Uğur Canpolat

  • 1Department of Cardiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Coronary Artery Disease
|October 31, 2012
PubMed

Insights

The prevalence of coronary artery disease (CAD) in patients with rheumatic valvular disease (RVD) is low overall. However, rheumatic aortic stenosis is linked to higher CAD rates, while aortic regurgitation shows a lower prevalence.

Area of Science:

  • Cardiology
  • Valvular Heart Disease
  • Coronary Artery Disease

Background:

  • Limited data exist on the association between rheumatic valvular disease (RVD) and coronary artery disease (CAD).
  • Investigating CAD prevalence in RVD patients undergoing valvular surgery is crucial.

Purpose of the Study:

  • To determine the prevalence of significant coronary artery disease (CAD) in patients with rheumatic valvular disease (RVD).
  • To explore the association between specific RVD types and CAD.

Main Methods:

  • Retrospective analysis of 1075 patients (61.2% women, mean age 53.2 years) who underwent coronary angiography before valvular surgery.
  • Data collected between January 2003 and May 2010.

Main Results:

  • Overall prevalence of significant CAD was 11.1%.
  • Significant CAD was more common in older patients with hypertension, smoking history, diabetes mellitus, and dyslipidemia.
  • Rheumatic aortic stenosis predicted higher CAD prevalence (OR 1.66), while aortic regurgitation showed an inverse association (OR 0.56).

Conclusions:

  • The prevalence of CAD in RVD patients is generally low.
  • Rheumatic aortic stenosis is associated with an increased prevalence of CAD.
  • Aortic regurgitation is associated with a lower prevalence of CAD.
Abstract

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