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Symptom clusters in children
Cheryl C Rodgers1, Mary C Hooke, Marilyn J Hockenberry
1Baylor College of Medicine/Texas Children's Hospital, Houston, Texas 77030, USA.
Insights
Understanding pediatric symptom clusters is crucial. This review highlights common symptoms like depression, anxiety, pain, and fatigue, and their interactions in various childhood diseases, emphasizing the need for further research.
Area of Science:
- Pediatric symptomology
- Symptom cluster research
Background:
- Previous research has identified and described symptoms in children with various diseases.
- Symptoms can have synergistic and/or antecedent effects that require evaluation.
- Limited evidence exists on symptom cluster research in pediatrics.
Purpose of the Study:
- To review current knowledge of symptoms across pediatric diseases.
- To highlight the importance and current state of symptom cluster research in pediatrics.
Main Methods:
- Literature review of pediatric symptom studies.
- Focus on identifying prevalent symptoms and their correlations.
- Analysis of studies examining symptom interactions.
Main Results:
- Depression and anxiety are the most studied symptoms, followed by pain, fatigue, and quality of life.
- Pain and fatigue are frequently analyzed for correlations and relationships with other symptoms.
- Commonly associated symptoms include sleep disturbances, anxiety, depression, anorexia, and nausea/vomiting.
Conclusions:
- Pediatric oncology is leading symptom cluster research, but it is in its early stages.
- Cluster analysis holds significant potential for advancing the science of pediatric symptomology.
- Future research should prioritize evaluating symptoms and their complex interactions.
Purpose Of Review:
Researchers have focused on identifying and describing symptom experiences among children with various diseases but symptoms can have a synergistic and/or an antecedent effect that must be evaluated. This review reports the current knowledge of symptoms among various pediatric diseases and highlights symptom cluster research.
Recent Findings:
Symptoms of depression and anxiety are the most prevalent variables studied across pediatric disease studies followed by pain, fatigue, and quality of life. Although previous pediatric symptom research provides a foundation for understanding the complexities of these symptoms, there is limited evidence on symptom cluster research in pediatrics. Pain and fatigue are the most common symptoms analyzed for correlations, and relationships among symptoms that have been evaluated in children with juvenile idiopathic arthritis, HIV, cancer, cardiac disease requiring an implantable cardioverter defibrillator, and at end of life. Pain and fatigue have been associated with sleep disturbances, anxiety, depression, anorexia, and nausea/vomiting.
Summary:
Pediatric oncology researchers are leading the way with symptom cluster studies; however, this work remains in the early stages. There is great potential to advance the state of the science with cluster analysis. Future research work should focus on evaluating symptoms and their interactions.
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