Related Experiment Videos
Spectacular skin nodules: cutaneous necrobiotic xanthogranuloma without paraproteinemia
Shimoni Kadakia1, Nitin Nadkarni, Sham Sonavane
1Rajawadi Hospital and Dr. D. Y. Patil Medical College, Mumbai, Maharashtra, India.
Abstract:
Necrobiotic xanthogranuloma (NXG) is a very rare, progressive variant of non-Langerhans cell histiocytosis. It is known to be associated with multisystem involvement and paraproteinemias. A 65-year-old female presented with chronic, slowly growing, asymptomatic periorbital nodules. The lesions had recurred after local excision elsewhere. No systemic involvement or paraproteinemias were detected. A provisional diagnosis of isolated cutaneous NXG was made which was confirmed by histopathology and immunohistochemistry staining. The lesions were surgically excised with excellent cosmetic and functional results. There was no recurrence over a period of 9 months. To our knowledge, this is the second case of NXG reported from India and the first without any systemic manifestations.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Endocarditis II: Clinical Features of Infective Endocarditis
Nephrotic Syndrome I : Introduction