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Disseminated cryptococcosis presenting with generalized lymphadenopathy.
Kandathil Joseph Philip1, Rupinder Kaur, Mohan Sangeetha
1Departments of Pathology, Christian Medical College and Hospital, Ludhiana, Punjab, India.
Journal of Cytology
|November 1, 2012
Summary
Cryptococcosis can affect lymph nodes, mimicking tuberculosis in immunocompromised patients. This case highlights disseminated cryptococcosis diagnosed via fine needle aspiration cytology and fungal culture.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Immunocompromised Host Research
Background:
- Cryptococcosis is a significant opportunistic fungal infection.
- Commonly affects the respiratory and central nervous systems.
- Immunocompromised individuals are at higher risk.
Observation:
- A 32-year-old immunocompromised male presented with generalized lymphadenopathy.
- Clinical suspicion was high for tuberculous lymphadenitis.
- Lymph node involvement is an uncommon presentation of cryptococcosis.
Findings:
- Diagnosis of disseminated cryptococcosis was confirmed.
- Fine needle aspiration cytology was instrumental in diagnosis.
- Fungal isolation on culture further supported the diagnosis.
Implications:
- This case underscores the importance of considering fungal infections in lymphadenopathy.
- Highlights the diagnostic utility of fine needle aspiration cytology.
- Emphasizes the need for awareness of unusual presentations of cryptococcosis in immunocompromised patients.
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