Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

High-Performance Liquid Chromatography: Types of Detectors

High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...

Labeling DNA Probes

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular-Extrusion-Driven Halogen Homogenization for Efficient Perovskite-Silicon Tandem Solar Cells.

Angewandte Chemie (International ed. in English)·2026

Same author

A novel activation-related gene P158 is essential for evagination and early development of Echinococcus multilocularis protoscoleces.

Parasites & vectors·2026

Same author

Structural Homology Solid Additives Enhancing Crystallization Thermodynamics for Constructing Ordered Fibrillar Network Toward 20.22% Efficiency Layer-by-Layer Organic Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

AI-Assisted Digital Single-Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo-Oxidative Damage in High-Photon-Flux Enzymology.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Electrostatic-Driven Nucleobase Discrimination by Covalent Organic Framework Nanosheets for Deoxyribonucleic Acid Methylation Profiling.

Journal of the American Chemical Society·2026

Same author

Brain-Derived Extracellular Vesicle Subpopulations: from Bulk Measurements to Single-Entity Assays.

JACS Au·2026

Search research articles

Related Experiment Video

Updated: May 17, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

A multi-parameter decoupling method with a Lamb wave sensor for improving the selectivity of label-free liquid

Lianqun Zhou¹, Yihui Wu, Ming Xuan

¹Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhoulq@sibet.ac.cn

Sensors (Basel, Switzerland)

|November 1, 2012

Summary

This study introduces a novel liquid multi-parameter decoupling method using a single Lamb wave sensor. It accurately determines liquid density and viscosity, enhancing biosensor selectivity and unknown liquid identification.

Keywords:

Lamb wave sensor density determination of multi-parameters sound velocity viscosity

More Related Videos

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

Published on: November 23, 2015

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Published on: February 4, 2018

Related Experiment Videos

Last Updated: May 17, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

Published on: November 23, 2015

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Design and Characterization Methodology for Efficient Wide Range Tunable MEMS Filters

Published on: February 4, 2018

Area of Science:

Materials Science
Acoustics
Chemical Sensing

Background:

Label-free biosensors often face challenges with selectivity.
Accurate liquid property detection (density, sound velocity, viscosity) is crucial for various applications.

Purpose of the Study:

To develop a single Lamb wave sensor method for multi-parameter liquid analysis.
To decouple and determine liquid density and viscosity simultaneously.
To improve selectivity in label-free biosensing.

Main Methods:

Utilizing antisymmetric (A(01), A(03)) and symmetric (S(0)) Lamb wave modes.
Employing the A(0) mode for density determination.
Using S(0) mode amplitude shifts, correlated with density, to determine viscosity.

Main Results:

Demonstrated the distinct roles of different Lamb wave modes in liquid property detection.
Successfully identified liquid density using the A(0) mode.
Calculated liquid viscosity based on density and S(0) mode amplitude shifts.

Conclusions:

The presented method enables high-sensitivity, label-free detection of multiple liquid parameters.
This approach offers a potential solution for selectivity issues in biosensors.
It provides a pathway for distinguishing unknown liquids efficiently.