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Related Experiment Videos

IgA nephritis associated with plasminogen abnormalities.

Y Kitamoto1, M Nakayama, Y Sakata

  • 13rd Department of Internal Medicine, Kumamoto University Medical School, Japan.

Clinical Nephrology
|February 1, 1990
PubMed
Summary

Hereditary plasminogen abnormalities, including dysplasminogenemia and plasminogen deficiency, may accelerate IgA nephritis progression. Decreased fibrinolysis and renal vascular injury synergistically promote kidney arteriosclerosis in these patients.

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Area of Science:

  • Nephrology
  • Hematology
  • Genetics

Background:

  • Immunoglobulin A (IgA) nephritis is a common cause of glomerulonephritis.
  • Hereditary plasminogen abnormalities can affect fibrinolysis.
  • Renal vascular changes are observed in IgA nephritis progression.