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Updated: May 17, 2026
04:41
Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
Published on: July 3, 2018
Enteroviruses in acute myocardial infarction
T Mohamadpoor1, Ms Nabavinia, A Gholoobi
1Microbiology and Virology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Iranian Journal of Public Health
|November 1, 2012
Summary
Enterovirus genomic RNA was detected in 2.6% of acute myocardial infarction (MI) patients. Further research is needed to confirm the role of enteroviruses in MI pathogenesis.
Area of Science:
- Cardiology
- Virology
- Infectious Diseases
Background:
- Human enteroviruses (EVs) are implicated as potential risk factors in myocardial infarction (MI) pathogenesis.
- Evaluating the presence of enterovirus genomic RNA in peripheral blood of acute MI patients is crucial.
Purpose of the Study:
- To assess the prevalence of enterovirus genomic RNA in the peripheral blood of patients diagnosed with acute myocardial infarction (MI).
Main Methods:
- Reverse transcription-polymerase chain reaction (RT-PCR) was employed to detect enterovirus genomic RNA.
- Peripheral blood samples from 115 acute MI patients were analyzed.
Main Results:
- Enterovirus genomic RNA was detected in 3 out of 115 patient samples (2.6%) using RT-PCR.
- The study population comprised patients with a mean age of 63.5 years, and 38.3% were female.
Conclusions:
- A notable prevalence of enterovirus was observed in patients with myocardial infarction.
- Additional investigations are required to establish a definitive causal relationship between enteroviruses and MI.
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