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Updated: May 17, 2026

Conventional BODIPY Conjugates for Live-Cell Super-Resolution Microscopy and Single-Molecule Tracking
Published on: June 8, 2020
Oligothienyl-BODIPYs: red and near-infrared emitters
Arnaud Poirel1, Antoinette De Nicola, Raymond Ziessel
1Laboratoire de Chimie Organique et Spectroscopies Avancées (LCOSA), UMR 7515 au CNRS, École de Chimie, Polymères et Matériaux de Strasbourg (ECPM), 25, Rue Becquerel, 67087 Strasbourg, Cedex 02, France.
Abstract:
The synthesis of unsymmetrical 3,5-dioligothienyl-BODIPY derivatives and their optical and redox properties are reported. The key step is the monobromination of the 2,6-dimethyl-3,5-dithienyl-BODIPY at the α position of the thiophene moiety. The additional thiophene modules are attached by palladium-catalyzed cross-coupling reactions. Increasing the number of modules on each side of the BODIPY core progressively shifts the absorption to 677 nm and the emission to 769 nm.
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