Computerised algorithm of tumour-associated markers to monitor haematopoietic malignancy

Hexosaminidase, polyamines and lipid-bound sialic acid are a few tumour-associated markers which are significantly elevated both in urine and serum of patients with haematopoietic malignancy, in direct correlation to dedifferentiation. Our computer database incorporates these parameters and predicts the clinical response based on the baseline values of these tumour-associated markers. This completely menu-driven user-friendly database can be routinely applied in tumour management and can access a billion records. The results of our evaluation confirm that most clinical assessments by a physician working blind are in agreement with the computer prediction, thus encouraging the use of microcomputers in patient management.