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Updated: May 17, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Ultralong-range phase imaging with orthogonal dispersive spectral-domain optical coherence tomography
Chuan Wang1, Zhihua Ding, Shengtao Mei
1State Key Lab of Modern Optical Instrumentation, Zhejiang University, Hangzhou, China.
A novel spectral-domain optical coherence tomography (SDOCT) system achieves ultrahigh spectral resolution and an unprecedented 80 mm imaging depth. This advancement enhances signal-to-noise ratio for detailed imaging applications.
Area of Science:
- Optics and Photonics
- Biomedical Imaging
- Spectroscopy
Background:
- Spectral-domain optical coherence tomography (SDOCT) is a key imaging modality.
- Improving spectral resolution and imaging depth in SDOCT systems remains a significant challenge.
Purpose of the Study:
- To develop an orthogonal dispersive SDOCT system with enhanced spectral resolution and extended imaging depth.
- To demonstrate the system's capability for quantitative phase imaging.
Main Methods:
- Utilized a spectrometer combining a virtually-imaged phased array (VIPA) and a diffraction grating for 2D dispersion.
- Employed a 2D CCD camera for spectral acquisition.
- Integrated the spectrometer into an SDOCT system.
Main Results:
- Achieved ultrahigh spectral resolution of 0.002 nm over a 50 nm free spectrum range.
- Realized a spectral sampling rate up to ~10^5.
- Demonstrated an imaging depth exceeding 80 mm, the longest reported for SDOCT.
- Obtained a high signal-to-noise ratio.
- Successfully performed quantitative phase imaging of optical components.
Conclusions:
- The developed orthogonal dispersive SDOCT system offers superior spectral resolution and imaging depth.
- This advancement enables high-performance SDOCT imaging and quantitative phase analysis.
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