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Updated: May 17, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Rational antibiotic prescribing. Challenges and successes]
1Zentrum Infektiologie und Reisemedizin, Medizinische Universitätsklinik, Hugstetterstrasse 55, Freiburg, Germany. kern@if-freiburg.de
Effective antibiotic stewardship requires robust data and trained professionals, which are currently lacking in Germany. Initiatives like GERMAP and Antibiotic Stewardship (ABS) programs show progress, but long-term investment in specialized training is crucial for future success in controlling antibiotic resistance.
Area of Science:
- Public Health
- Infectious Disease Control
- Healthcare Policy
Context:
- Prudent antibiotic prescribing is vital in both hospital and ambulatory settings.
- Germany faces challenges in meeting prerequisites for effective antibiotic policies, notably a lack of trained personnel.
- Existing national programs show progress but require sustained support.
Purpose:
- To assess the current state of antibiotic use and resistance control in Germany.
- To identify challenges and successes in implementing antibiotic stewardship strategies.
- To outline future perspectives and investment needs for combating antibiotic resistance.
Summary:
- Germany's antibiotic stewardship efforts are hindered by insufficient data and trained personnel.
- Initiatives like the German Antibiotic Resistance Monitoring System (GERMAP) and Antibiotic Stewardship (ABS) programs demonstrate progress.
- Future success hinges on evaluating guideline adherence, developing quality indicators, and investing in specialized training for healthcare professionals.
Impact:
- Highlights critical gaps in Germany's antibiotic resistance control infrastructure.
- Underscores the need for enhanced training and certification in infectious diseases and infection control.
- Provides a roadmap for strengthening national strategies against antibiotic resistance through targeted investment and policy development.
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