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Updated: May 17, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Rapid symptomatic and radiographic evolution after presumed spontaneous infarction of a meningioma
Derek R Johnson1, Timothy J Kaufmann
1Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA. johnson.derek1@mayo.edu
Abstract:
Meningiomas are extremely common benign extra-axial brain tumors. When meningiomas present clinically, they typically cause subacute symptoms such as headache. Rarely, meningiomas become acutely symptomatic due to tumor necrosis, which may occur spontaneously or as a result of global hypoperfusion. Here, we describe an elderly man who experienced a rapid subacute decline after meningioma infarction. Computed tomography and magnetic resonance imaging obtained in this case demonstrate the evolution of a benign-appearing meningioma into a ring-enhancing lesion with significant surrounding cerebral edema in <2 weeks. After the resection of a WHO grade 1 meningioma with central necrosis, the patient made a good clinical recovery.
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