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A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence
Published on: October 11, 2018
Clostridium perfringens type A fatal acute hemorrhagic gastroenteritis in a dog
Ben J Schlegel1, Tony Van Dreumel, Durda Slavić
1Department of Pathobiology (Schlegel, Prescott), University of Guelph, Guelph, Ontario N1G 2W1.
Abstract:
The morning after participating in a dog show, a 2-year-old Pomeranian dog was found dead in a pool of bloody feces. Necropsy revealed hemorrhagic gastroenteritis of the entire gastrointestinal tract, with many Gram-positive bacilli on the surface and in the lumen and crypts of the intestine. Enterotoxin-positive type A Clostridium perfringens were isolated in large numbers. This dramatic case of fatal C. perfringens gastroenteritis highlights the need to better understand the role of this bacterium in enteric disease of dogs.
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